Amin2, maqsood ahmad 1 and alamgeer 1 department of pharmacy, university of sargodha, sargodha40100, pakistan 2department of physiology and pharmacology university of agriculture, faisalabad pakistan. Pdf threat status of rheum emodi a study in selected. Unit a 125, patparganj industrial area delhi 110092 unit b 476, patparganj industrial area, delhi 110092. Rheum emodi wall polygonaceae is a food plant with medicinal value restricted to the temperate, subalpine, and alpine zones of the himalayas in altitudes ranging from 2,800 to 3,800 m. Rheum emodin inhibits enterovirus 71 viral replication and affects the host cell cycle environment skip to main content thank you for visiting. Rheum emodi or himalayan rhubarb is a perennial herb belongs to family. Theraputic values of rheum emodi sarvpreet singh, priyanka sharma. Species are native to eastern europe, southern and eastern temperate asia, with a few reaching into northern tropical asia. Rheum emodi noun the noun rheum emodi has 1 sense 1. Pdf threat status of rheum emodi a study in selected cis. The present invention also relates to medicine composition with the extract as active component and the application of the extract and the medicine composition in treating hyperlipidemia and obesity. The rats had free access to standard pellet chow and water ad libitum throughout the experiment with the exception of some experiments see. Total of 95 bioactive compounds were obtained in methanol extract of r. Rheum webbianum royle is an important medicinal plant belonging to the family polygonaceae.
Geographical source habit and habitat 9820197 it is obtained both from wild and cultivated species grown in regions ranging from south east to china to tibet and korea. Effect of rheum emodi revand hindi on renal functions in. The plant majorly consists of pharmacologically and therapeutically significant free 1,8dihydroxy anthraquinones and their glycosides. Polygonaceae, english name rhubarb is a stout herb and distributed in the temperate and subtropical regions of asian countries, viz.
Primary rat hepatocyte monolayer cultures were used for in vitro studies. Rheum emodi being one of the most sought after species in the pharmaceutical industry, providing good dividends to the states from where it is procured, is rapidly declining in nature. Jul 03, 20 therefore, it has been identified top priority species for conservation and cultivation. Materials and methods the roots of rheum emodi wall commonly known as revand chini were purchased from an herbal dealer locally called as pansari. Seeds of rheum emodi, a threatened medicinal plant of northwestern himalaya collected from natural populations at the different regions of high altitude were germinated under different conditions by giving different treatments to form seedlings. Nov 28, 2006 in the present study, we selected two plants, namely sapindus mukorossi and rheum emodi, and investigated the inhibitory effect of these plant extracts against h pylori in vitro and in vivo. The disk diffusion method was used for in vitro studies and in vivo studies were performed on male wister rats. Micropropagation and conservation of rheum webbianum collected from zanaskar valley via tissue culture rheum webbianum is one of the famous and popular medicinal plant found in ladakh region. The present study is aimed at applying colouring component of rheum emodi on wool and silk followed by evaluating some. The ones marked may be different from the article in the profile. Antimicrobial activity of sapindus mukorossi and rheum.
Hepatoprotective activity of sapindus mukorossi and rheum emodi. Rheum emodi asian herb himalayan rhubarb, redveined pie plant, rheum australe, indian rhubarb genus rheum, rheum. In the current study, the populations of rheum emodi were collected from different locations and were analysed for emodin, aloeemodin, rhein by hplc method. Himalayan rhubarb, indian rhubarb, rheum australe, redveined pie plant type of. Rheum emodi wall has been reported to possess protective effect in many inflammatory diseases and oxidative stressrelated injuries. Comparative hplc analysis of emodin, aloe emodin p. Antioxidant and anticancer potentials of rheum emodi rhizome. Rheum is a genus of about 60 herbaceous perennial plants in the family polygonaceae. Rheum emodi is a medicinal plant of immense importance with a diverse pharmacological spectrum. Rheum emodi is an immensely useful medicinal herb of himalaya having remarkable antidiabetic and anticancerous activities reported mainly from rhizomatous portion of the plant. It commonly known as himalayan rhubarb, indian rhubarb and redveined pie plant.
Rheum acuminatum ornamental rhubarb this plant likes to grow in or near water, in summer it has red seedpods. Rheum officinale or rheum palmatum are grown in china whereas the other species rheum webbianum, rheum austrele, rheum emodi are native to india, pakistan or nepal. It is commonly known as himalayan rhubarb in english, revandchini in hindi, xu mi da huang in chinese, and lachhu or churtsa in ladakh. Antioxidant and anticancer potentials of rheum emodi. The body depends on liver to regulate, synthesize, store and secrete many important proteins and nutrients and to purify, transform and clear toxic substances. Rheum emodin inhibits enterovirus 71 viral replication and. The objective of this study was to determine antioxidant and cytotoxic efficacies of methanolic and aqueous extracts of rheum emodi wall. Pdf effect of rheum emodi revand hindi on renal functions.
Rheum emodi has been traditionally used to treat pathological ailments like fevers, ulcers, bacterial infections. It grows in the alpine zone on rocky soils, moraines and cervices 20. India is considered as one of the twelve megabiodiversity countries of the world which are enrich in vegetation. Low mounds of heavily veined leaves, rich red petioles, and upright, branched and spidery stems or red flowers to 4 feet 1.
Effect of rheum emodi revand hindi on renal functions in rats article pdf available in journal of ethnopharmacology 9612. Percentage yield of crude extract of rheum emodi solvent wt. Rheum emodi an indian variety of the chinese rhubarb plays a vital role in traditional chinese and indian forms of medicine. Phytochemical screening of rheum emodi rheum emodi tests methanolic aqueous. The present study reports gas chromatographic mass spectroscopic characterization of both the conventionally used part i. Rheum emodi polygonaceae, commonly known as revandchini, is the himalayan species of indian rhubarb found wild at an altitude of 400012 000 feet in kashmir, nepal, sikkim and bhutan. The renal effects of watersoluble ws and waterinsoluble wins portions of the alcoholic extract of revand hindi rheum emodi were investigated on cadmium chloride, mercuric chloride, potassium dichromate and gentamicininduced nephrotoxicity in rats and normal rats by monitoring the levels of urea nitrogen and creatinine in serum. Germanibility, conservation and cultivation of rheum emodi. Rheum webbianum is one of the famous and popular medicinal plant found in ladakh region. Roots of the indian rhubarb is darker, inferior in aroma, is a well known. Phytoconstituents and therapeutic uses of rheum emodi wall. Rheum emodi induces nitric oxide synthase activity in murine.
Highly endangered medicinal herb ruchi singh, tanuja tiwari and preeti chaturvedi abstract rheum emodi or indian rhubarb is one of the important medicinal herb used in chinese herbal medicine since 2700 bc and now days it is used in large number of pharmaceutical industries because of its highly. The species have large somewhat triangular shaped leaves with long, fleshy. Target 200 plants of rheum emodi in 10 sq km area natural habitat each of two areas of study. Barceloux, md history although the petioles of rhubarb leaves have been a food source in modern times, the dried root or rhizome has been used as a medicinal herb since the third millennium bc. Antiproliferative and apoptotic effects of rheum emodi on human. Rheum emodi synonyms, rheum emodi pronunciation, rheum emodi translation, english dictionary definition of rheum emodi. Phytochemical characterization of rhizome, fruit, leaf and.
This paper consists of literature of rheum emodi regarding its ethnobotany. Himalayan rhubarb, redveined pie plant, rheum australe, indian rhubarb. Rheum emodi definition of rheum emodi by the free dictionary. The large, somewhat triangular leaf blades are elevated on long, fleshy petioles. A watery or thin mucous discharge from the eyes or nose. A randomized single blind standard control study was conducted among 45 subjects of primary dysmenorrhea. Therefore, it has been identified top priority species for conservation and cultivation. This paper consists of literature of rheum emodi regarding its ethnobotany, folkloric uses, chemical properties and pharmacological studies. Polygonaceae buckwheat family medicinal use of himalayan rhubarb. An extract of rheum emodi, wherein rheum emodi emodi rhubarb extract is an aqueous extract or organic solvent extract, rhubarbbased tibetan side as raw materials, the organic solvent is extracted from the aqueous solvent, solvent recovery obtained dry paste. Potential antioxidant anthraquinones isolated from rheum.
The liver is the key organ of metabolism and detoxification. Emodi forte is a simple yet powerful trinity of herbs rheum emodi, berberis aristata and oscimum sanctum. Effect of rhubarb rheum emodi in primary dysmenorrhoea. Besides having the abovementioned pharmacological properties, it has been used as an ingredient of many herbal formulations, which are used for the treatment of various diseases, in particular the regulation of blood fat, hepatitis and cancer. Cytotoxicity of rheum emodin, artemisinin and astragaloside via mtt assay. Micropropagation and conservation of rheum webbianum. Powdered rhizomes are sprinkled over ulcers for quick healing. Curative effect of extracts of sapindus mukorossi and. The flowers are small, greenishwhite, and borne in large compound leafy inflorescences. Uses, side effects, interactions, dosage, and warning. Antimicrobial activity of sapindus mukorossi and rheum emodi.
It has been used in various traditional systems as laxative, tonic, diuretic and to treat fever, cough. Rheum australe, synonym rheum emodi, is a flowering plant in the family polygonaceae. This study aims to investigate antioxidant power of stilbenoids from r. Efficacy of rewandchini rheum emodi in the management of. Rheum emodi offered by green earth products pvt ltd, a leading supplier of raw medicinal herbs in greater kailash, part 1, new delhi. India kashmir, assam, sikkim, nepal, bhutan and china. It is one of the most widely used herbs in chinese medicine. Nov 14, 2016 cytotoxicity of rheum emodin, artemisinin and astragaloside via mtt assay. Curative effect of extracts of sapindus mukorossi and rheum. Rheum emodi asian herb himalayan rhubarb, redveined pie plant, rheum australe, indian rhubarb genus rheum, rheum rhubarb rhubarb plant, rhubarb. It is also reported to be a potent antiinflammatory drug. It is a medicinal herb used in the indian unani system of medicine, and formerly in the european system of medicine where it was traded as indian rhubarb.
Rheum emodi polygonaceae, a plant found in the western himalayas, is a source of anthraquinone derivatives, including emodin, aloe emodin, physcion, chrysophanol, rhein, emodin glycoside and chrysophanol glycoside verma et al. Safoofepathar phori spp is an unani polyherbomineral formulation and has been used in unani system of medicine for its antiurolithiatic activity 2. Rheum emodi is a perennial stout herb found between 2,8003,600 m in alpine zone of rocky soil. Hepatoprotective effect of rheum emodi roots revand chini and akseerejigar against paracetamolinduced hepatotoxicity in rats m. Rheum emodi or himalayan rhubarb is a perennial herb belongs to family polygonaceae. Estimation of anthraquinones and their glycosides from rhizomes. It has been used in various traditional systems as laxative, tonic, diuretic and to treat fever, cough, indigestion, menstrual disorder since antiquity. Pdf india is one of the twelve megabiodiversity countries of the world. Free fulltext pdf articles from hundreds of disciplines, all in one place potential antioxidant anthraquinones isolated from rheum emodi showing nematicidal activity against meloidogyne incognita pdf paperity. Rheum emodi page 162 introduction rheum emodi wall. Acceleration of procaspase3 maturation and cell migration. It has been used in various traditional systems as laxative, tonic.
Estimation of anthraquinones and their glycosides from. Rheum emodi is a stout herb, endemic to the himalayan region distributed in the temperate and subtropical region from kashmir to sikkim at an elevation of 28003000m in india. Rhubarb and oxalosis rheum species pdf free download. Besides, compounds from all the populations were correlated with in vitro raised plants of r. Antifungal activity of anthraquinone derivatives from. Indian rhubarb, which is official in indian pharmacopoeia, consists of the dried rhizomes of r. The present study aimed to investigate the phytoconstituents and specific anticancer activities of rheum emodi rhizome, a known food source used locally to treat various ailments. Hepatoprotective activity of sapindus mukorossi and rheum.
Rhubarb has been successfully grown in certain parts of assam nadkarni, 1954. The aggressive nature of estrogen receptor ernegative breast cancer subtype obligates for innovative targeted therapies. Ex meissn therapeutic usesr heum emodi is a mild purgative, astringent, tonic, laxative, stomachic, and aperient. Petroleum ether extracts hot phr and cold pcr of r. Onehundred grams of powdered form of roots was obtained mechanically with a china herb. Medicinal rhubarb consists of the dried rhizome and root of r. To study the curative effect of sapindus mukorossi and rheum emodi extracts in ccl4 induced liver cirrhosis in male rats. Phytochemical analysis and antimicrobial activity of rheum. Morphological characteristics rewand chini is a perennial stout herb, 1. The present work focuses on estimation of the free anthraquinones and their glycosides from indian rhubarb rheum emodi viz.
Qualitative and quantitative analysis of anthraquinone. In ayurvedic and unani systems of medicine, rheum emodi re commonly known as revand chini or rhubarb is an important medicinal plant. The present invention relates to rheum emodi nall extract obtained with water or organic solvent and through extraction, merging extracted liquid and recovering solvent. Rhubarb has a long and proven history of herbal usage, its main effect being a positive and balancing effect upon the whole digestive system. Rhizomes of rheum emodi have been used in unani system of medicine either alone or as an ingredient of many polyherbal formulations for treating various ailments. Rhubarb is a group of herbaceous perennial plants that grow from thick short rhizomes, comprising the genus rheum. In india, it is distributed in altitudes ranging from 2800 to 3800 m in the. It is endemic to western and central himalayan region. Seeds of rheum emodi, a threatened medicinal plant of northwestern himalaya collected from natural populations at the different regions of high altitude were germinated under different conditions by giving. Department of chemistry, chandigarh university, gharuan, mohali. A very potent blood sugar lowering herb, rheum emodi is also called the indian rhubarb. Rheum emodi green earth products pvt ltd exporter in. The aim of this study was to assess efficacy of rewandchini rheum emodi in the management of primary dysmenorrhea. This cited by count includes citations to the following articles in scholar.
Hepatoprotective effect of rheum emodi roots revand chini. Materials and methods collection of wild germplasm of rheum emodi. To study the hepatoprotective capacity of sapindus mukorossi s. Antioxidant activities of stilbenoids from rheum emodi wall. It is disease free and hardy all across the country canada. A inhibitory effects of rheum emodin rheu on mrc5 cell growth. The company was incorporated in 2005 and is registered with indiamart.
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